Journal
ANNUAL REVIEW OF PUBLIC HEALTH
Volume 25, Issue -, Pages 155-197Publisher
ANNUAL REVIEWS
DOI: 10.1146/annurev.publhealth.25.101802.123020
Keywords
pesticides; epidemiology; exposure assessment; chronic disease; adult health
Categories
Funding
- NATIONAL CANCER INSTITUTE [ZIACP010119, Z01CP010119] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES [ZIAES044007, Z01ES044007] Funding Source: NIH RePORTER
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Pesticides are widely used in agricultural and other settings, resulting in continuing human exposure. Epidemiologic studies indicate that, despite premarket animal testing, current exposures are associated with risks to human health. In this review, we describe the routes of pesticide exposures occurring today, and summarize and evaluate the epidemiologic studies of pesticide-related carcinogenicity and neurotoxicity in adults. Better understanding of the patterns of exposure, the underlying variability within the human population, and the links between the animal toxicology data and human health effects will improve the evaluation of the risks to human health posed by pesticides. Improving epidemiology studies and integrating this information with toxicology data will allow the human health risks of pesticide exposure to be more accurately judged by public health policy makers.
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