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Neural development and the ontogeny of central nervous system tumors

Journal

NEURON GLIA BIOLOGY
Volume 1, Issue -, Pages 127-133

Publisher

CAMBRIDGE UNIV PRESS
DOI: 10.1017/S1740925X04000286

Keywords

embryonal tumors; medulloblastoma; astrocytoma; stem cells; cerebellum; cerebellar granule cells

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Funding

  1. National Institutes of Health
  2. Children's Brain Tumor Foundation
  3. Kyle Mullarkey Medulloblastoma Research Fund
  4. EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT [P30HD018655] Funding Source: NIH RePORTER
  5. NATIONAL CANCER INSTITUTE [R01CA109467] Funding Source: NIH RePORTER

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Recent evidence argues that the oncogenesis and growth of CNS tumors occurs through dysregulated molecular and cellular mechanisms of neural development. New insights have emerged that have had a significant impact on both research and treatment of these cancers.

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