Journal
PHYSIOLOGICAL REVIEWS
Volume 84, Issue 1, Pages 69-85Publisher
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physrev.00016.2003
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Funding
- NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE [R37NS032405, R01NS032405] Funding Source: NIH RePORTER
- NINDS NIH HHS [NS-32405] Funding Source: Medline
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Synaptic ultrastructure is critical to many basic hypotheses about synaptic transmission. Various aspects of synaptic ultrastructure have also been implicated in the mechanisms of short-term plasticity. These forms of plasticity can greatly affect synaptic strength during ongoing activity. We review the evidence for how synaptic ultrastructure may contribute to facilitation, depletion, saturation, and desensitization.
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