4.5 Article

Reduction of N-(alkoxy(aryl)methyl)benzamide Compounds by a Hantzsch Ester 1,4-Dihydropyridine Using Pd/C as a Catalyst

Journal

CATALYSIS LETTERS
Volume 126, Issue 3-4, Pages 361-366

Publisher

SPRINGER
DOI: 10.1007/s10562-008-9631-1

Keywords

N-(alkoxy(aryl)methyl)benzamide compounds; Palladium on carbon; Reduction; Hantzsch ester 1; 4-dihydropyridine

Funding

  1. National Natural Science Foundation of China [20702023]
  2. Ministry of Education of China [20070730040]

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Pd/C-catalyzed transfer hydrogenation with Hantzsch ester1,4-dihydropyridine was found to be very effective for the selective reduction of N-(alkoxy(aryl)methyl) benzamide compounds to the corresponding benzamides. The reaction conditions, solvent effects, and reaction mechanism were discussed in the present work.

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