Journal
CATALYSIS COMMUNICATIONS
Volume 26, Issue -, Pages 6-10Publisher
ELSEVIER
DOI: 10.1016/j.catcom.2012.05.004
Keywords
Asymmetric organocatalysis; Aldol reaction; Carbohydrate; Recoverable catalyst
Categories
Funding
- National Natural Science Foundation of China [21076052]
- Science and Technology Plan of Zhejiang Province [2011C24004]
- Key Sci-tech Innovation Team of Zhejiang Province [2010R50017]
Ask authors/readers for more resources
The catalytic activity of novel carbohydrate-derived prolinamide in the enantioselective aldol reactions has been examined for the first time. The organocatalyst 2b was found to be an efficient organocatalyst for the asymmetric aldol reaction in water. This organocatalyst is applicable to the reactions of a wide range of aromatic aldehydes with cyclic and acyclic ketones in high yields (up to 98%). These reactions exhibit high anti/syn ratios (up to 99%) and excellent enantioselectivities (up to 99%). Importantly, the catalyst can be easily recovered and recycled with only a slight decrease in enantioselectivity after five cycles. Crown Copyright (C) 2012 Published by Elsevier B.V. All rights reserved.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available