4.6 Article

Identification of promoter regions involved in cell- and developmental stage-specific osteopontin expression in bone, kidney, placenta, and mammary gland: An analysis of transgenic mice

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 19, Issue 1, Pages 78-88

Publisher

WILEY
DOI: 10.1359/jbmr.2004.19.1.78

Keywords

osteopontin; transgenic mice; promoter; green fluorescent protein; cis-acting element

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Cell-specific expression of GFP under the control of different lengths of the osteopontin promoter in transgenic mice identified the positive and negative regulatory regions for respective cell types. The results provide new insights for physiological and pathological expression of the osteopontin gene.

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