Journal
CATALYSIS COMMUNICATIONS
Volume 10, Issue 5, Pages 625-626Publisher
ELSEVIER SCIENCE BV
DOI: 10.1016/j.catcom.2008.11.004
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Funding
- National Science Foundation for a RUI (Research in Undergraduate Institutions) [0650682]
- Illinois Wesleyan University for an Artistic and Scholarly
- Division Of Chemistry
- Direct For Mathematical & Physical Scien [0650682] Funding Source: National Science Foundation
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The bismuth bromide catalyzed synthesis of a range of substituted tetrahydroquinoline derivatives via a three component coupling reaction between Substituted anilines and enol ethers is reported. Bismuth compounds are attractive for use as catalysts because of their remarkably low toxicity. Bismuth bromide is relatively inexpensive and easy to handle, and hence preferable to other corrosive catalysts previously used for synthesis of tetrahydroquinoline derivatives. (C) 2008 Elsevier B.V. All rights reserved.
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