4.6 Article

beta-adrenergic blockers reduce the risk of fracture partly by increasing bone mineral density: Geelong osteoporosis study

Journal

JOURNAL OF BONE AND MINERAL RESEARCH
Volume 19, Issue 1, Pages 19-24

Publisher

AMER SOC BONE & MINERAL RES
DOI: 10.1359/JBMR.0301214

Keywords

beta-blocker; fracture; bone densitometry; population studies; case-control studies

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This population-based study documented beta-blocker use in 59/569 cases with incident fracture and 112/775 controls. OR for fracture associated with beta-blocker use was 0.68 (95%CI, 0.49-0.96). beta-Blockers were associated with higher BMD at the total hip (2.5%) and UD forearm (3.6%) after adjusting for age, anthropometry, and thiazide use. beta-Blocker use is associated with reduced fracture risk and higher BMD.

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