4.6 Article

Efficient synthesis of 1,5-benzodiazepines catalyzed by silica supported 12-tungstophosphoric acid

Journal

CATALYSIS COMMUNICATIONS
Volume 9, Issue 15, Pages 2496-2502

Publisher

ELSEVIER SCIENCE BV
DOI: 10.1016/j.catcom.2008.07.004

Keywords

silica supported; 12-tungstophosphoric acid; 1,5-benzodiazepine; o-phenylenediamine; heteropoly acid

Funding

  1. Yazd University Research Council

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Silica supported 12-tungstophosphoric acid efficiently catalyzes the reaction of o-phenylenediamine with ketones under solvent free condition to afford the corresponding 1,5-benzodiazepines in good to excellent yields. The catalyst can be recovered by simple filtration and reused. (C) 2008 Elsevier B.V. All rights reserved.

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