4.8 Article

Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S hygroscopicus

Journal

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
Volume 43, Issue 19, Pages 2551-2553

Publisher

WILEY-V C H VERLAG GMBH
DOI: 10.1002/anie.200453764

Keywords

biosynthesis; macrocycles; natural products; polyketides

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