A Suzuki-Miyaura coupling mediated deprotection as key to the synthesis of a fully lipidated malarial GPI disaccharide

Ligandless palladium-catalyzed Suzuki - Miyaura coupling converted an inert p-bromobenzyl ether to a DDQ-labile p( 3,4-dimethoxyphenyl) benzyl ether in the presence of azide functionality and this strategy serves as a key step for the convergent synthesis of a fully lipidated malaria GPI disaccharide.