4.7 Article

Affinity mass spectrometry from a tailored porous silicon surface

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 18, Pages 2108-2109

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b408200a

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Funding

  1. NCRR NIH HHS [RR-15066] Funding Source: Medline
  2. NATIONAL CENTER FOR RESEARCH RESOURCES [R01RR015066] Funding Source: NIH RePORTER

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The development of chemically stable porous silicon (pSi) materials for DIOS (Desorption/Ionization on Silicon) mass spectrometry, covalent linkers cleaved in the DIOS laser pulse, and efficient methods for bond formation to immobilized species, allows for on-chip affinity purification and mass detection.

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