4.7 Article

Ligand-free Heck reactions using low Pd-loading

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 14, Pages 1559-1563

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b406719n

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Activated and non-activated aryl bromides undergo smooth ligand-less Heck reactions, provided low amounts of palladium salts such as Pd(OAc)(2) are used (ideally 0.01-0.1 mol%). This industrially viable process appears to involve palladium nanoparticles.

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