4.8 Article

The Pfam protein families database

Journal

NUCLEIC ACIDS RESEARCH
Volume 32, Issue -, Pages D138-D141

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/nar/gkh121

Keywords

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Funding

  1. BBSRC [BB/F010435/1] Funding Source: UKRI
  2. Biotechnology and Biological Sciences Research Council [BB/F010435/1] Funding Source: Medline
  3. Howard Hughes Medical Institute Funding Source: Medline
  4. Medical Research Council [G0100305] Funding Source: Medline
  5. Medical Research Council [MC_U137761446] Funding Source: Medline
  6. Wellcome Trust [WT077044/Z/05/Z, 087656] Funding Source: Medline
  7. Wellcome Trust [087656] Funding Source: Medline
  8. Wellcome Trust [WT077044/Z/05/Z] Funding Source: Medline

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Pfam is a large collection of protein families and domains. Over the past 2 years the number of families in Pfam has doubled and now stands at 6190 (version 10.0). Methodology improvements for searching the Pfam collection locally as well as via the web are described. Other recent innovations include modelling of discontinuous domains allowing Pfam domain definitions to be closer to those found in structure databases. Pfam is available on the web in the UK (http://www.sanger.ac.uk/ Software/Pfam/), the USA (http://pfam.wustl.edu/), France (http://pfam.jouy.inra.fr/) and Sweden (http:// Pfam.cgb.ki.se/).

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