4.4 Article

Transcriptome analysis of the response of Pseudomonas aeruginosa to hydrogen peroxide

Journal

JOURNAL OF BACTERIOLOGY
Volume 186, Issue 1, Pages 248-252

Publisher

AMER SOC MICROBIOLOGY
DOI: 10.1128/JB.186.1.248-252.2004

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Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H2O2 and untreated controls. The data indicate that the early response of P. aeruginosa to H2O2 consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.

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