Journal
JOURNAL OF CLINICAL MICROBIOLOGY
Volume 42, Issue 1, Pages 449-452Publisher
AMER SOC MICROBIOLOGY
DOI: 10.1128/JCM.42.1.449-452.2004
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An enzyme-linked immunosorbent assay to diagnose Chagas' disease by a serological test was performed with Trypanosoma cruzi recombinant antigens (JL8, MAP, and TcPo). High sensitivity (99.4%) and specificity (99.3%) were obtained when JL8 was combined with MAP (JM) and tested with 150 serum samples from chagasic and 142 nonchagasic individuals. Moreover, JM also diagnosed 84.2% of patients in the acute phase of T. cruzi infection.
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