Simultaneous acquisition of gradient-echo and asymmetric spin-echo for single-shot z-shim: Z-SAGA

This article describes the Z-SAGA pulse sequence, a technique for recovering susceptibility losses in EPI images for neuroimaging applications. The pulse sequence is based on an asymmetric spin echo EPI sequence and acquires a gradient echo image and an asymmetric spin echo image in a single shot. For one of the images, a z-shim gradient pulse is applied to compensate for susceptibility-related field distortions. The two images are combined to form an image with reduced signal loss. This sequence is simple to implement and experimentally demonstrated to be effective for BOLD imaging. (C) 2003 Wiley-Liss, Inc.