4.6 Article

The IFCC recommendation on estimation of reference intervals. The RefVal Program

Journal

CLINICAL CHEMISTRY AND LABORATORY MEDICINE
Volume 42, Issue 7, Pages 710-714

Publisher

WALTER DE GRUYTER GMBH
DOI: 10.1515/CCLM.2004.121

Keywords

computer program; reference values; statistics

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The International Federation of Clinical Chemistry (IFCC) published between 1987-91 a series of six recommendations on reference values in laboratory medicine. This paper reviews the history and scope of the fifth part of these recommendations. This fifth recommendation deals with statistical methods used for analysis of reference values and estimation of reference intervals. The RefVal program, which implements the recommended method, is also described.

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