4.4 Article

Expression of DC-SIGN in human foreskin may facilitate sexual transmission of HIV

Journal

JOURNAL OF CLINICAL PATHOLOGY
Volume 57, Issue 1, Pages 77-78

Publisher

B M J PUBLISHING GROUP
DOI: 10.1136/jcp.57.1.77

Keywords

-

Categories

Ask authors/readers for more resources

This study demonstrates that the human immunodeficiency virus (HIV) binding C-type lectin DC-SIGN is coexpressed with CD4 and CCR5 on dendritic cells/macrophages in human foreskin. It is hypothesised that DC-SIGN may contribute to the sexual transmission of HIV in the foreskin, by enabling infection of permissive cells in cis and/or in trans.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.4
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available