Journal
DRUGS
Volume 64, Issue 15, Pages 1697-1714Publisher
ADIS INT LTD
DOI: 10.2165/00003495-200464150-00009
Keywords
sodium phosphate; colon cleansing; bowel cleansing; pharmacodynamics; therapeutic use; tolerability
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Oral sodium phosphate solution (Fleet(R) Phospho-soda(R), Casen-Fleet(R) Fosfosoda(R)) is a low-volume, hyperosmotic agent used as part of a colorectal-cleansing preparation for surgery, x-ray or endoscopic examination. The efficacy and tolerability of oral sodium phosphate solution was generally similar to, or significantly better than, that of polyethylene glycol (PEG) or other colorectal cleansing regimens in patients preparing for colonoscopy, colorectal surgery or other colorectal-related procedures. Generally, oral sodium phosphate solution was significantly more acceptable to patients than PEG or other regimens. The use of this solution should be considered in most patients (with the exception of those with contraindications) requiring colorectal cleansing.
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