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Making sense of nonsense: the evolution of selenocysteine usage in proteins

Journal

GENOME BIOLOGY
Volume 6, Issue 6, Pages -

Publisher

BMC
DOI: 10.1186/gb-2005-6-6-221

Keywords

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Funding

  1. NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM068077] Funding Source: NIH RePORTER
  2. NIGMS NIH HHS [R01 GM068077] Funding Source: Medline

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A recent analysis of sequences derived from organisms in the Sargasso Sea has revealed a surprisingly different set of selenium- containing proteins than that previously found in sequenced genomes and suggests that selenocysteine utilization has been lost by many groups of organisms during evolution.

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