Journal
EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
Volume 93, Issue 4, Pages 435-439Publisher
SPRINGER
DOI: 10.1007/s00421-004-1235-x
Keywords
pulmonary circulation; resistance; temperature; rat
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The effect of different temperatures of perfusing fluid was tested on the pulmonary circulation of the rat. With increasing temperature, a decrease in overall pulmonary vascular resistance was observed, which depended on the associated reductions of arterial, venous and capillary vascular resistances. The highest sensitivity to temperature changes was exhibited by the venous segment. The overall sensitivity of pulmonary vessels to temperature caused a reduction in hydraulic resistance of about 1% for each 1degreesC temperature increment. Compliance of pulmonary vessels increased when perfusate temperature was increased from between 25 and 35degreesC to 45degreesC, probably due to a direct effect of temperature on the stiffness of the vessel walls.
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