Journal
ARCHIVES OF PHARMACAL RESEARCH
Volume 28, Issue 1, Pages 34-38Publisher
PHARMACEUTICAL SOC KOREA
DOI: 10.1007/BF02975132
Keywords
Firmiana simplex; sterculiaceae; benzodioxane lignan; neolignan; antipsychotic effect
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A new neolignan, named simplidin was isolated from the the n-butanol extract of stem of Firmiana simplex, together with six known compounds, scopoletin (1), syrigaresinol (2), aquillochin (3), nitidanin (4), tamarixetin 3-rhamnoside (6), and quercitrin (7). On the basis of spectral and chemical evidence, simplidin (5) was determined to be rel-(7R,8R)-4,5,9,9'-tetrahydroxy-3,3'dimethoxy-7-O-5',8-O-4'-neolignan. All the six compounds were also isolated for the first time from this plant.
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