Journal
RNA
Volume 11, Issue 1, Pages 7-13Publisher
COLD SPRING HARBOR LAB PRESS, PUBLICATIONS DEPT
DOI: 10.1261/rna.7203605
Keywords
signal recognition particle; SRP; nomenclature; comparative sequence analysis; secondary structure
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Funding
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM049034] Funding Source: NIH RePORTER
- NIGMS NIH HHS [GM-49034, R01 GM049034] Funding Source: Medline
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The signal recognition particle (SRP) is a cytosolic ribonucleoprotein complex that guides secretory proteins to biological membranes in all organisms. The SRP RNA is at the center of the structure and function of the SRP. The comparison of the growing number of SRP RNA sequences provides a rich source for gaining valuable insight into the composition, assembly, and phylogeny of the SRP. In order to assist in the continuation of these studies, we propose an SRP RNA nomenclature applicable to the three divisions of life.
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