Journal
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES
Volume 4, Issue 3, Pages 251-253Publisher
SPRINGERNATURE
DOI: 10.1039/b416418k
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Irradiation of amelanotic melanoma B78H1 cells in the presence of liposome-delivered Ni(II)-octabutoxy-naphthalocyanine with a Q-switched Ti: sapphire laser operated in a pulsed mode (850 nm, 30 ns pulses, 10 Hz, 120 mJ pulse 1) promotes a photothermal sensitization process leading to extensive cell inactivation. The photoprocess occurs with identical efficiency in N-2-saturated and air-equilibrated media, indicating that this photosensitization modality does not require the presence of oxygen.
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