Journal
PURE AND APPLIED CHEMISTRY
Volume 77, Issue 1, Pages 179-184Publisher
WALTER DE GRUYTER GMBH
DOI: 10.1351/pac200577010179
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Several substituted alpha-alkoxy phenyl propionic acids were synthesized, and their hypotriglyceridemic properties were evaluated in Swiss albino mice. Some of the compounds showed excellent triglyceride- and cholesterol-lowering properties even at a dose of 1 mg/kg. 2,5-Substituted pyrrole-containing heterocycles were among the most potent alkoxy propionic acid class of compounds. These compounds also showed excellent antidiabetic activities in animal models.
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