Journal
CARDIOLOGY IN REVIEW
Volume 17, Issue 6, Pages 283-286Publisher
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/CRD.0b013e3181b3fe0d
Keywords
apelin; APJ receptor; renin-angiotensin system
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This article focuses oil a newly discovered bioactive peptide, termed apelin, as it relates to the cardiovascular system. Apelin, through its G-protein coupled receptor, seems to primarily exert effects in blood pressure control, and may play a role in heart failure and in myocardial reperfusion injury. In addition, at least some of apelin's effects appear to stein from an interaction with the renin-angiotensin system. Apelin may provide a target for drug treatment of cardiovascular disease.
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