Journal
MECHANISMS OF AGEING AND DEVELOPMENT
Volume 126, Issue 1, Pages 171-175Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.mad.2004.09.019
Keywords
proteomics; genome; microarrays; high-throughput; discovery research
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Protein microarrays containing thousands of proteins arrayed at high density can be prepared and probed for a wide variety of activities. thereby allowing the large scale analysis of many proteins simultaneously. In addition to identifying the activities of many previously uncharacterized proteins, protein microarrays can reveal new activities of well-characterized proteins, thus providing new insights about the functions of these proteins. Below. we describe the construction and use of protein microarrays and their applications using yeast as a model system. (C) 2004 Elsevier Ireland Ltd. All rights reserved.
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