Selenium protective activity against aflatoxin B-1 adverse affects on Drosophila melanogaster

The aim of this work was to investigate the effects of AFB(1) and AFB(1) + Se4+ various developmental stages of Drosophila melanogaster were investigated. Both different concentrations of AFB(1) and Se4+ applied with AFB(1) were fed during the flies developmental period (egg, larva and pupae). When F-1 progeny of control and application groups were compared with each other, AFB(1) was found to have extending the process of metamorphosis (aid decreasing the total number of offsprings. But, these negative effects were inhibited with selenium treatment at different concentrations (4.0 and 8.0 ppm). These results suggested that selenium could effectively inhibit AFB(1) induced abnormalities of the developmental stages of D. melanogaster.