Journal
TRENDS IN PHARMACOLOGICAL SCIENCES
Volume 26, Issue 1, Pages 1-3Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tips.2004.11.001
Keywords
-
Categories
Ask authors/readers for more resources
Huntington's disease is caused by a polyglutamine expansion in the protein huntingtin. Several studies suggest that huntingtin and its associated protein HAP1 participate in intracellular trafficking and that polyglutamine expansion affects vesicular transport. A study now provides new evidence that HAP1 is also involved in the endocytosis of membrane receptors. These studies offer insight into the normal function of HAP1 and its involvement in Huntington's disease.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available