Journal
COLLECTION OF CZECHOSLOVAK CHEMICAL COMMUNICATIONS
Volume 70, Issue 12, Pages 2038-2052Publisher
INST ORGANIC CHEM AND BIOCHEM
DOI: 10.1135/cccc20052038
Keywords
Serratula coronata L. (Asteraceae); ecdysteroids; ecdysone 22-acetate; steroids; phytochemistry; natural compounds isolation; NMR spectroscopy
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Eleven phytoecdysteroids have been isolated and identified from the low polarity fractions of Serratula coronata juice by a combination of column chromatography and HLPC. Four of them are new, i.e. ecdysone 22-acetate 7, (25S)-inokosterone 26-acetate 9, 20,22-O-(R-ethylidene)-20- hydroxyecdysone 10 and 20,22-O-(R-ethylidene)-ajugasterone C 11. The biological activity of these new ecdysteroids in the Drosophila melanogaster B-II cell bioassay is reported.
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