Related references
Note: Only part of the references are listed.Protection of Humans by Plant Glucosinolates: Efficiency of Conversion of Glucosinolates to Isothiocyanates by the Gastrointestinal Microflora
Jed W. Fahey et al.
CANCER PREVENTION RESEARCH (2012)
Cancer stem cells: In the line of fire
Malcolm R. Alison et al.
CANCER TREATMENT REVIEWS (2012)
D,L-sulforaphane-induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc
Kozue Sakao et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2012)
Bim contributes to phenethyl isothiocyanate-induced apoptosis in breast cancer cells
Eun-Ryeong Hahm et al.
MOLECULAR CARCINOGENESIS (2012)
Critical Role of p53 Upregulated Modulator of Apoptosis in Benzyl Isothiocyanate-Induced Apoptotic Cell Death
Marie Lue Antony et al.
PLOS ONE (2012)
Benzyl Isothiocyanate Causes FoxO1-Mediated Autophagic Death in Human Breast Cancer Cells
Dong Xiao et al.
PLOS ONE (2012)
Phenethyl isothiocyanate suppresses inhibitor of apoptosis family protein expression in prostate cancer cells in culture and in vivo
Kozue Sakao et al.
PROSTATE (2012)
Anti-angiogenic effects of dietary isothiocyanates: Mechanisms of action and implications for human health
Breeze E. Cavell et al.
BIOCHEMICAL PHARMACOLOGY (2011)
Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice
Eun Ji Kim et al.
BREAST CANCER RESEARCH AND TREATMENT (2011)
Benzyl Isothiocyanate Inhibits Epithelial-Mesenchymal Transition in Cultured and Xenografted Human Breast Cancer Cells
Anuradha Sehrawat et al.
CANCER PREVENTION RESEARCH (2011)
Proteins as binding targets of isothiocyanates in cancer prevention
Lixin Mi et al.
CARCINOGENESIS (2011)
Selective Depletion of Mutant p53 by Cancer Chemopreventive Isothiocyanates and Their Structure-Activity Relationships
Xiantao Wang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2011)
Benzyl Isothiocyanate (BITC) and Phenethyl Isothiocyanate (PEITC)-Mediated Generation of Reactive Oxygen Species Causes Cell Cycle Arrest and Induces Apoptosis via Activation of Caspase-3, Mitochondria Dysfunction and Nitric Oxide (NO) in Human Osteogenic Sarcoma U-2 OS Cells
Chang-Lin Wu et al.
JOURNAL OF ORTHOPAEDIC RESEARCH (2011)
Chemopreventative Potential of the Cruciferous Vegetable Constituent Phenethyl Isothiocyanate in a Mouse Model of Prostate Cancer
Anna A. Powolny et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2011)
Sulforaphane Increases Drug-mediated Cytotoxicity Toward Cancer Stem-like Cells of Pancreas and Prostate
Georgios Kallifatidis et al.
MOLECULAR THERAPY (2011)
Exemestane for Breast-Cancer Prevention in Postmenopausal Women
Paul E. Goss et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Benzyl Isothiocyanate Suppresses Pancreatic Tumor Angiogenesis and Invasion by Inhibiting HIF-α/VEGF/Rho-GTPases: Pivotal Role of STAT-3
Srinivas Reddy Boreddy et al.
PLOS ONE (2011)
Notch Activation by Phenethyl Isothiocyanate Attenuates Its Inhibitory Effect on Prostate Cancer Cell Migration
Su-Hyeong Kim et al.
PLOS ONE (2011)
Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention
Ka Lung Cheung et al.
AAPS JOURNAL (2010)
Inhibition of Autophagy Potentiates Sulforaphane-Induced Apoptosis in Human Colon Cancer Cells
Takeshi Nishikawa et al.
ANNALS OF SURGICAL ONCOLOGY (2010)
A matter of balance between life and death Targeting reactive oxygen species (ROS)-induced autophagy for cancer therapy
Spencer B. Gibson
AUTOPHAGY (2010)
Determination of new biomarkers to monitor the dietary consumption of isothiocyanates
Anoop Kumar et al.
BIOMARKERS (2010)
In vivo modulation of 4E binding protein 1 (4E-BP1) phosphorylation by watercress: a pilot study
Sharifah S. Syed Alwi et al.
BRITISH JOURNAL OF NUTRITION (2010)
Intake of Cruciferous Vegetables Modifies Bladder Cancer Survival
Li Tang et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2010)
Sulforaphane Inhibits Constitutive and Interleukin-6-Induced Activation of Signal Transducer and Activator of Transcription 3 in Prostate Cancer Cells
Eun-Ryeong Hahm et al.
CANCER PREVENTION RESEARCH (2010)
p53-Independent Apoptosis by Benzyl Isothiocyanate in Human Breast Cancer Cells Is Mediated by Suppression of XIAP Expression
Su-Hyeong Kim et al.
CANCER PREVENTION RESEARCH (2010)
p66Shc Is Indispensable for Phenethyl Isothiocyanate-Induced Apoptosis in Human Prostate Cancer Cells
Dong Xiao et al.
CANCER RESEARCH (2010)
Selective Autophagy in Cancer Development and Therapy
Ivan Dikic et al.
CANCER RESEARCH (2010)
Differential in vivo mechanism of chemoprevention of tumor formation in azoxymethane/dextran sodium sulfate mice by PEITC and DBM
Ka Lung Cheung et al.
CARCINOGENESIS (2010)
Sulforaphane inhibits 4-aminobiphenyl-induced DNA damage in bladder cells and tissues
Yi Ding et al.
CARCINOGENESIS (2010)
Sensitization of Non-small Cell Lung Cancer Cells to Cisplatin by Naturally Occurring Isothiocyanates
Anthony J. Di Pasqua et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
New Biomarkers for Monitoring the Levels of Isothiocyanates in Humans
Anoop Kumar et al.
CHEMICAL RESEARCH IN TOXICOLOGY (2010)
Sulforaphane, a Dietary Component of Broccoli/Broccoli Sprouts, Inhibits Breast Cancer Stem Cells
Yanyan Li et al.
CLINICAL CANCER RESEARCH (2010)
Phenethyl Isothiocyanate Inhibits Oxidative Phosphorylation to Trigger Reactive Oxygen Species-mediated Death of Human Prostate Cancer Cells
Dong Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Inhibition of Human Breast Cancer Xenograft Growth by Cruciferous Vegetable Constituent Benzyl Isothiocyanate
Renaud Warin et al.
MOLECULAR CARCINOGENESIS (2010)
Phenethyl Isothiocyanate Sensitizes Androgen-Independent Human Prostate Cancer Cells to Docetaxel-Induced Apoptosis In Vitro and In Vivo
Dong Xiao et al.
PHARMACEUTICAL RESEARCH (2010)
Differential Response of Normal (PrEC) and Cancerous Human Prostate Cells (PC-3) to Phenethyl Isothiocyanate-Mediated Changes in Expression of Antioxidant Defense Genes
Anna A. Powolny et al.
PHARMACEUTICAL RESEARCH (2010)
Inhibition of hypoxia inducible factor by phenethyl isothiocyanate
Xiu-Hong Wang et al.
BIOCHEMICAL PHARMACOLOGY (2009)
Sulforaphane Inhibits Prostate Carcinogenesis and Pulmonary Metastasis in TRAMP Mice in Association with Increased Cytotoxicity of Natural Killer Cells
Shivendra V. Singh et al.
CANCER RESEARCH (2009)
Prevention of Mammary Carcinogenesis in MMTV-neu Mice by Cruciferous Vegetable Constituent Benzyl Isothiocyanate
Renaud Warin et al.
CANCER RESEARCH (2009)
Atg5 Regulates Phenethyl Isothiocyanate-Induced Autophagic and Apoptotic Cell Death in Human Prostate Cancer Cells
Ajay Bommareddy et al.
CANCER RESEARCH (2009)
Targeting Protein Kinase C (PKC) and Telomerase by Phenethyl Isothiocyanate (PEITC) Sensitizes PC-3 Cells Towards Chemotherapeutic Drug-Induced Apoptosis
Sutapa Mukherjee et al.
JOURNAL OF ENVIRONMENTAL PATHOLOGY TOXICOLOGY AND ONCOLOGY (2009)
The Role of STAT-3 in the Induction of Apoptosis in Pancreatic Cancer Cells by Benzyl Isothiocyanate
Ravi P. Sahu et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2009)
Isothiocyanates sensitize the effect of chemotherapeutic drugs via modulation of protein kinase C and telomerase in cervical cancer cells
Sutapa Mukherjee et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2009)
D,L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells
Su-Hyeong Kim et al.
MOLECULAR CANCER THERAPEUTICS (2009)
Causes and consequences of microRNA dysregulation in cancer
Carlo M. Croce
NATURE REVIEWS GENETICS (2009)
Cellular Responses to Cancer Chemopreventive Agent D,L-Sulforaphane in Human Prostate Cancer Cells Are Initiated by Mitochondrial Reactive Oxygen Species
Dong Xiao et al.
PHARMACEUTICAL RESEARCH (2009)
Pharmacokinetics and Pharmacodynamics of Broccoli Sprouts on the Suppression of Prostate Cancer in Transgenic Adenocarcinoma of Mouse Prostate (TRAMP) Mice: Implication of Induction of Nrf2, HO-1 and Apoptosis and the Suppression of Akt-dependent Kinase Pathway
Young-Sam Keum et al.
PHARMACEUTICAL RESEARCH (2009)
Consumption of raw cruciferous vegetables us inversely associated with Bladder cancer risk
Li Tang et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2008)
Multi-targeted prevention of cancer by sulforaphane
John D. Clarke et al.
CANCER LETTERS (2008)
Inhibition of urinary bladder carcinogenesis by broccoli sprouts
Rex Munday et al.
CANCER RESEARCH (2008)
Chemoprevention of cancer by isothiocyanates and anthocyanins: Mechanisms of action and structure-activity relationship
C. Fimognari et al.
CURRENT MEDICINAL CHEMISTRY (2008)
Benzyl Isothiocyanate Targets Mitochondrial Respiratory Chain to Trigger Reactive Oxygen Species-dependent Apoptosis in Human Breast Cancer Cells
Dong Xiao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Chemoprevention of familial adenomatous polyposis in ApcMin/+ mice by phenethyl isothiocyanate (PEITC)
Tin Oo Khor et al.
MOLECULAR CARCINOGENESIS (2008)
Murine Prostate Cancer Inhibition by Dietary Phytochemicals-Curcumin and Phenyethylisothiocyanate
Avantika Barve et al.
PHARMACEUTICAL RESEARCH (2008)
MicroRNA expression alterations are linked to tumorigenesis and non-neoplastic processes in pancreatic ductal adenocarcinoma
A. E. Szafranska et al.
ONCOGENE (2007)
Molecular basis for chemoprevention by sulforaphane: a comprehensive review
N. Juge et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2007)
Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line
Anna Herman-Antosiewicz et al.
MOLECULAR CANCER THERAPEUTICS (2007)
Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1
Jing Hu et al.
CANCER RESEARCH (2007)
Phenethyl isothiocyanate inhibits angiogenesis in vitro and ex vivo
Dong Xiao et al.
CANCER RESEARCH (2007)
Sulforaphane suppresses angiogenesis and disrupts endothelial mitotic progression and microtubule polymerization
Steven J. T. Jackson et al.
VASCULAR PHARMACOLOGY (2007)
Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak
Dong Xiao et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by sulforaphane, a natural product derived from cruciferous vegetable
Rong Hu et al.
CARCINOGENESIS (2006)
Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters
Yuichi Kuroiwa et al.
CANCER LETTERS (2006)
Expression of clusterin in prostate cancer correlates with Gleason score but not with prognosis in patients undergoing radical prostatectomy without neoadjuvant hormonal therapy
Hideaki Miyake et al.
UROLOGY (2006)
Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
Dunyaporn Trachootham et al.
CANCER CELL (2006)
Sulforaphane causes autophagy to inhibit release of cytochrome c and apoptosis in human prostate cancer cells
Anna Herman-Antosiewicz et al.
CANCER RESEARCH (2006)
Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion
Joell J. Gills et al.
CANCER LETTERS (2006)
Inhibition of angiogenesis and endothelial cell functions are novel sulforaphane-mediated mechanisms in chemoprevention
E Bertl et al.
MOLECULAR CANCER THERAPEUTICS (2006)
Effects of Indole-3-Carbinol and phenethyl isothiocyanate on colon carcinogenesis induced by azoxymethane in rats
AYA Plate et al.
CARCINOGENESIS (2006)
Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apc(min) mice
MC Myzak et al.
FASEB JOURNAL (2006)
Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: A clinical phase I study
Theresa A. Shapiro et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2006)
Challenge and promise: roles for clusterin in pathogenesis, progression and therapy of cancer
B Shannan et al.
CELL DEATH AND DIFFERENTIATION (2006)
Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China
TW Kensler et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2005)
Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice
CC Conaway et al.
CANCER RESEARCH (2005)
Suppression of NF-κB and NF-κB-regulated gene expression by sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells
CJ Xu et al.
ONCOGENE (2005)
Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species
SV Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Limited tumor-initiating activity of phenylethyl isothiocyanate by promotion with sodium L-ascorbate in a rat two-stage urinary bladder carcinogenesis model
H Takagi et al.
CANCER LETTERS (2005)
Bax and Bak are required for apoptosis induction by sulforaphane, a cruciferous vegetable-derived cancer chemopreventive agent
S Choi et al.
CANCER RESEARCH (2005)
beta-phenylethyl isothiocyanate mediated apoptosis; contribution of Bax and the mitochondrial death pathway
P Rose et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2005)
Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization
SJT Jackson et al.
CARCINOGENESIS (2004)
Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells
SK Srivastava et al.
CARCINOGENESIS (2004)
Effects of benzyl-, phenethyl-, and α-naphthyl isothiocyanates on P-glycoprotein- and MRP1-mediated transport
K Hu et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2004)
Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C
SV Singh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
The chemopreventive agent phenethyl isothiocyanate sensitizes cells to Fas-mediated apoptosis
JM Pullar et al.
CARCINOGENESIS (2004)
Benzyl isothiocyanate modifies expression of the G(2)/M arrest-related genes
N Miyoshi et al.
BIOFACTORS (2004)
Phenethyl isothiocyanate inhibits nitrosamine carcinogenesis in a model for study of oral cancer chemoprevention
DB Solt et al.
CANCER LETTERS (2003)
Reversibility of proliferative lesions and induction of non-papillary tumors in rat urinary bladder treated with phenylethyl isothiocyanate
S Sugiura et al.
CARCINOGENESIS (2003)
Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation
K Okazaki et al.
CANCER SCIENCE (2003)
Benzyl isothiocyanate: an effective inhibitor of polycyclic aromatic hydrocarbon tumorigenesis in A/J mouse lung
SS Hecht et al.
CANCER LETTERS (2002)
Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine
E Tseng et al.
PHARMACEUTICAL RESEARCH (2002)
Epithelial-mesenchymal transitions in tumour progression
JP Thiery
NATURE REVIEWS CANCER (2002)
Isothiocyanates as cancer chemopreventive agents: Their biological activities and metabolism in rodents and humans
CC Conaway et al.
CURRENT DRUG METABOLISM (2002)
Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors
JW Fahey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine
K Okazaki et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2002)
Continued breast cancer risk reduction in postmenopausal women treated with raloxifene: 4-year results from the MORE trial
JA Cauley et al.
BREAST CANCER RESEARCH AND TREATMENT (2001)
Dose-dependent promotion by phenylethyl isothiocyanate, a known chemopreventer, of two-stage rat urinary bladder and liver carcinogenesis
K Ogawa et al.
NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2001)
Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate
FL Chung et al.
CARCINOGENESIS (2000)
Effects of phenethyl isothiocyanate and benzyl isothiocyanate, individually and in combination, on lung tumorigenesis induced in A/J mice by benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
SS Hecht et al.
CANCER LETTERS (2000)
Share Paper
