Journal
TRENDS IN NEUROSCIENCES
Volume 28, Issue 9, Pages 501-506Publisher
ELSEVIER SCIENCE LONDON
DOI: 10.1016/j.tins.2005.07.002
Keywords
-
Categories
Ask authors/readers for more resources
Multiple system atrophy (MSA) is a fatal neurodegenerative disorder presenting with autonomic failure and motor impairment, primarily comprising L-doparesistant parkinsonism but occasionally involving cerebellar ataxia. These features result from progressive multisystem neuronal loss that is associated with oligodendroglial alpha-synuclein inclusions. The growing number of animal models for MSA reflects the search for a preclinical test-bed for elucidating MSA pathogenesis and for developing novel therapeutic interventions. Here, the currently available MSA animal models will be reviewed and leads for future research will be identified.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available