Journal
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH
Volume 33, Issue 1, Pages 55-60Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/147323000503300104
Keywords
sevoflurane; isoflurane; propofol; inhalational anaesthesia; intravenous anaesthesia; geriatric; recovery
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We compared the effects of sevoflurane, isoflurane and propofol infusions on postoperative recovery criteria in geriatric patients. Sixty patients aged > 65 years, classified as American Society of Anesthesiologists (ASA) group 1 or 2 and undergoing gynaecological or urological procedures were randomized equally into three groups. Group 1 received 1 minimum alveolar concentration (MAC) sevoflurane in a 50% O-2/N2O mixture and group 2 received I MAC isoflurane in a 50% O-2/N2O mixture. Group 3 received a 50% O-2/N2O mixture plus propofol total intravenous anaesthesia (8 mg/kg for the first 30 min, followed by 6 mg/kg for maintenance). Recovery criteria comprising the times to spontaneous eye opening, extubation, response to verbal stimuli and orientation were recorded following the discontinuation of anaesthesia. Recovery times were significantly shorter in groups 1 and 3 compared with group 2. We conclude that sevoflurane and propofol had similar effects on recovery criteria and were associated with a faster recovery than isoflurane.
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