Journal
JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
Volume 16, Issue 4, Pages 489-503Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1163/1568562053700219
Keywords
hydrogels; poly(vinyl alcohol); poly(vinyl pyrrolidone); ion uptake; protein; compression
Ask authors/readers for more resources
The effect of two simulated biological environments (protein-free and protein-containing) on ion uptake and physical properties of PVA/PVP hydrogels were explored in this work. It was found that over the immersion period in both media, wet mass of the hydrogels decreased and compressive moduli increased, likely due to increased polymer content with water loss as the hydrogels equilibrated with water. These changes were independent of polymer content and immersion medium. However, dry mass of the hydrogels increased dramatically when immersed in protein-free medium, changing only moderately in protein-containing medium. The increase in dry mass was attributed to ion uptake from immersion medium, as confirmed by EDXA. We postulate that differences between ion uptake in protein-free versus protein-containing medium is likely the result of serum proteins in the protein-containing medium adsorbing to the surface, inhibiting transport of ions into the hydrogel.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available