Journal
PARKINSONISM & RELATED DISORDERS
Volume 11, Issue 6, Pages 381-386Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.parkreldis.2005.06.005
Keywords
hypersexuality; Parkinson's disease; parkinsonism; multiple system atrophy
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Pathological hypersexuality developed in 13 patients with PD and two patients ultimately diagnosed clinically with MSA. Hypersexuality began within 8 months after starting dopamine agonist therapy in 14 of 15 cases, including four on agonist monotherapy. It resolved in the four cases where the agonist was stopped, despite continued levodopa therapy. This was not an isolated behavioral problem in most, with additional compulsive or addictive behaviors coinciding in nine patients (60%). A systematic literature review of pathological hypersexuality in PD revealed similar medication histories; combining these cases with our series, 26 of 29 patients (90%) were on adjuvant dopamine agonists. (c) 2005 Elsevier Ltd. All rights reserved.
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