Evolution of mechanisms of Ca2+-signaling: Role of calcium ions in signal transduction in prokaryotes

The review considers current concepts of mechanisms of Ca2+-signaling in cells of prokaryotes. Problems of structural-functional organization of the Ca2+-messenger system, mechanisms of membrane transport, and Ca2+ homeostasis are discussed. A special attention is paid to analysis of role of calcium ions and Ca2+-receptor proteins in regulation of intracellular processes in bacteria.