4.2 Article

The rheology of blood flow in a branched arterial system

Journal

APPLIED RHEOLOGY
Volume 15, Issue 6, Pages 398-405

Publisher

KERSCHENSTEINER VERLAG GMBH
DOI: 10.1515/arh-2005-0020

Keywords

hemorheology; Newtonian model; non-Newtonian models; wall shear stress; atherosclerosis; thrombosis; wall shear stress; recirculation zone

Categories

Funding

  1. NCRR NIH HHS [P41 RR006009-150278] Funding Source: Medline
  2. NEI NIH HHS [R03 EY013756, R03 EY013756-03] Funding Source: Medline
  3. NIBIB NIH HHS [K01 EB000270-05] Funding Source: Medline
  4. NATIONAL CENTER FOR RESEARCH RESOURCES [P41RR006009] Funding Source: NIH RePORTER
  5. NATIONAL EYE INSTITUTE [R03EY013756] Funding Source: NIH RePORTER
  6. NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING [K01EB000270] Funding Source: NIH RePORTER

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Blood flow rheology is a complex phenomenon. Presently there is no universally agreed upon model to represent the viscous property of blood. However, under the general classification of non-Newtonian models that simulate blood behavior to different degrees of accuracy, there are many variants. The power law, Casson and Carreau models are popular non-Newtonian models and affect hemodynamics quantities under many conditions. In this study, the finite volume method is used to investigate hemodynamics predictions of each of the models. To implement the finite volume method,the computational fluid dynamics software Fluent 6.1 is used In this numerical study the different hemorheological models are found to predict different results of hemodynamics variables which are known to impact the genesis of atherosclerosis and formation of thrombosis. The axial velocity magnitude percentage difference Of Up to 2 % and radial velocity difference up to go % is found at different sections of the T-junction geometry. The size of flow recirculation zones and their associated separation and reattachment point's locations differ for each model. The wall shear stress also experiences up to 12 % shift in the main tube. A velocity magnitude distribution of the grid cells shows that the Newtonian model is close dynamically to the Casson model while the power law model resembles the Carreau model.

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