Journal
BIOSTATISTICS
Volume 6, Issue 1, Pages 119-143Publisher
OXFORD UNIV PRESS
DOI: 10.1093/biostatistics/kxh022
Keywords
cardiovascular disease; depression; DIC; general gyrowth mixuttre modeling; Gibbs sampling; label switching; model choice
Funding
- NATIONAL INSTITUTE OF MENTAL HEALTH [P30MH052129, R01MH061892] Funding Source: NIH RePORTER
- NIMH NIH HHS [R01 MH061892-01A2, R01 MH061892, R01-MH-61892, P30 MH052129-06, P30-MH2129] Funding Source: Medline
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Positive and negative affect data are often collected over time in psychiatric care settings, yet no generally accepted means are available to relate these data to useful diagnoses or treatments. Latent class analysis attempts data reduction by classifying subjects into one of K unobserved classes based on observed data. Latent class models have recently been extended to accommodate longitudinally observed data. We extend these approaches in a Bayesian framework to accommodate trajectories of both continuous and discrete data. We consider whether latent class models might be used to distinguish patients on the basis of trajectories of observed affect scores. reported events, and presence or absence of clinical depression.
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