4.5 Article

Albizosides D and E, two new cytotoxic triterpene saponins from Albizia chinensis

Journal

CARBOHYDRATE RESEARCH
Volume 345, Issue 13, Pages 1877-1881

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2010.05.024

Keywords

Albizia chinensis; Triterpene saponin; Albizoside D; Albizoside E; Cytotoxic activity

Funding

  1. National Fund for Distinguished Young Scholars [30625040]
  2. National Science and Technology Project of China [2009ZX09311-004]

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Two oleanane-type triterpene saponins, named albizosides D and E (1 and 2), together with a known compound, Julibroside J(8) (3), were isolated from the stem bark of Albizia chinensis. The structures of compounds 1 and 2 were established by 1D, 2D NMR experiments, and chemical methods, and they showed moderate cytotoxic activity against a small panel of human tumor cell lines. (C) 2010 Elsevier Ltd. All rights reserved.

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