4.5 Article

Identification of an acetyl disulfide derivative in the synthesis of thiosialosides

Journal

CARBOHYDRATE RESEARCH
Volume 345, Issue 1, Pages 160-162

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2009.10.017

Keywords

Thiosialoside; Sialoside; Sialic acid; Disulfide

Funding

  1. EPSRC
  2. Association for International Cancer Research
  3. Yorkshire Cancer Research
  4. EPSRC [EP/D06418X/1] Funding Source: UKRI
  5. Engineering and Physical Sciences Research Council [EP/D06418X/1] Funding Source: researchfish

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The first report of the formation of an acetyl disulfide sialoside during the synthesis of thioglycosides is described. This compound is a by-product in the synthesis of the 2-thioacetyl sialoside commonly used in thioglycoside preparation. Our investigations into the identification of this novel disulfide are described. (C) 2009 Elsevier Ltd. All rights reserved.

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