Journal
CARBOHYDRATE RESEARCH
Volume 344, Issue 10, Pages 1167-1174Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carres.2009.04.024
Keywords
Scabiosaponins; Bidesmosidic oleanolic acid saponins; One-pot sequential glycosylation; Trichloroacetimidates; p-Toluenethioglycosides
Funding
- Natural Science Foundation of China [30701046]
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The first synthesis of scabiosaponins E (1), F (2), and G (3), three new oleanolic acid saponins with strong inhibitory activity on pancreatic lipase isolated from the Chinese traditional medicinal herb Scabiosa tschiliensis, was efficiently achieved in an one-pot strategy under the combined use of glycosyl trichloro-acetimidates and p-toluene 1-thioglycosides (STol) as donors. (C) 2009 Published by Elsevier Ltd.
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