Journal
CARBOHYDRATE POLYMERS
Volume 106, Issue -, Pages 148-153Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2014.01.100
Keywords
Heparin; LMWHs; Enoxaparin; Depolymerization; Pre-filled syringe
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Anti-coagulants are one of the most important categories in healthcare therapeutics. For healthcare professionals dealing in cases of in-vivo blood clotting problems. Heparin and low molecular weight heparins (LMWHs) would be the first choice of drugs. This review represents an overview of the LMWHs, their importance over heparin and enlightens the advancements. In addition to these, different methods used for preparation and purification are discuss in terms of production and synthesis. Worldwide availability in pre-filled syringe, market, manufacturers and suppliers drug interactions, adverse drug reactions, in-vitro study, freezing/thawing process and structural differences of LMWHs are also focused upon in this review. (C) 2014 Elsevier Ltd. All rights reserved.
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