4.7 Article

Preparation and characterization of inclusion complexes of naringenin with β-cyclodextrin or its derivative

Journal

CARBOHYDRATE POLYMERS
Volume 98, Issue 1, Pages 861-869

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2013.07.010

Keywords

Naringenin; Cyclodextrin; Inclusion complex; Characterization; Inclusion mode

Funding

  1. Natural Science Foundation of China [21162042, 30960460]
  2. Natural Science Foundation of Yunnan Province [2010CD090, 2012FB113]
  3. Program for Innovative Research Team (in Science and Technology) in University of Yunnan Province (IRTSTYN)
  4. Program for Teaching Team of Chemistry Core Curriculum in University of Yunnan Province [0401-2001019014]

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The inclusion complexation behavior, characterization and binding ability of naringenin with beta-cyclodextrin and its derivatives were investigated in both solution and the solid state by means of XRD, DSC, SEM, H-1 and 2D NMR and UV-vis spectroscopy. The results showed that the water solubility and thermal stability of naringenin were obviously increased in the inclusion complex with cyclodextrins.This satisfactory water solubility and high thermal stability of the naringenin/CD complexes will be potentially useful for their application as herbal medicines or healthcare products. (C) 2013 Elsevier Ltd. All rights reserved.

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