Journal
CURRENT ANALYTICAL CHEMISTRY
Volume 1, Issue 1, Pages 85-92Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1573411052948479
Keywords
enantiomer separation; chiral mobile phase; chiral coated phase; hydrophobically coated phase
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O-Benzyl-(S)-serine is a new selector for chiral ligand-exchange chromatography which has proved to be effective in the analytical separation of some natural and unnatural underivatized amino acids with fair to good separation and resolution factors. Both chiral mobile phase (CMP) and hydrophobically coated chiral stationary phase (CSP) approaches were successfully employed. A not completely clarified mechanism of chiral recognition is discussed.
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