Hydrothermal synthesis of bacterial cellulose/AgNPs composite: A green route for antibacterial application

Antibacterial materials based on cellulose have been widely used in many fields. In this work, an environmentally benign and facile approach for production of silver nanoparticles (AgNPs) was proposed for the first time by hydrothermal synthesis using bacterial cellulose (BC) as both the reducing and stabilizing agent, without any chemical reagents introduced. Some key reaction parameters were optimized to achieve a high antibacterial activity of the BC/AgNPs composite. Under the optimal conditions, a small size and a narrow distribution of AgNPs, 17.1 +/- 5.9 nm, was formed on the BC matrix, with a silver content of 1.78% (w/w) and a MIC value of 1.30 x 10(-4) mu g/CFU. Moreover, a sustained release of silver and a prolonged antibacterial performance of the composite against Staphylococcus aureus were found over a long period time of 72 h, which were important for practical applications. (C) 2011 Elsevier Ltd. All rights reserved.