Journal
CARBOHYDRATE POLYMERS
Volume 78, Issue 1, Pages 54-59Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.carbpol.2009.04.029
Keywords
Chitosan; Ag-loading nano-SiO2; Structure; Antibacterial activity
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Funding
- National Natural Science Foundation of China [50673072]
- Program for New Century Excellent Talent in University [NCET-06262]
- Natural Scientific Foundation of Shanxi [20050016]
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A crosslinked chitosan (CCTS) coated Ag-loading nano-SiO2 composite (CCTS-SLS) was prepared. The structures of CCTS-SLS were characterized by field emission scanning electron microscopy and X-ray photoelectron spectroscopy. The antibacterial properties of CCTS-SLS were measured as the minimal inhibitory concentration and the rate of bacterial growth. The experimental results indicate that the antibacterial activity of CCTS-SLS was affected by the mass ratio of SLS to chitosan, acetic acid concentration and crosslinking time. Moreover, CCTS-SLS exhibited high antibacterial activity against Escherichia coli and Staphylococcus aureus as a result of the coordinated action of CCTS and SLS. (C) 2009 Elsevier Ltd. All rights reserved.
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