Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 2, Pages 265-267Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b412221f
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Funding
- NATIONAL CANCER INSTITUTE [R37CA016954, R01CA016954] Funding Source: NIH RePORTER
- NATIONAL INSTITUTE OF GENERAL MEDICAL SCIENCES [R01GM045026, R29GM045026] Funding Source: NIH RePORTER
- NCI NIH HHS [CA16954] Funding Source: Medline
- NIGMS NIH HHS [GM 45026] Funding Source: Medline
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The experimental evidence presented in this manuscript suggest against the widely accepted single electron/proton transfer mechanism for P-450 catalyzed N-dealkylations and provides strong support for a hydrogen atom abstraction mechanism.
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