4.7 Article

Heck-type 5-endo-trig cyclization promoted by vinylic fluorines: synthesis of 5-fluoro-3H-pyrroles

Journal

CHEMICAL COMMUNICATIONS
Volume -, Issue 37, Pages 4684-4686

Publisher

ROYAL SOC CHEMISTRY
DOI: 10.1039/b510039a

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A 5-endo-trig alkene insertion proceeds under palladium catalysis via aminopalladium species starting from 3,3-difluoro-allyl ketone O-pentafluorobenzoyloximes, providing a facile access to 5-fluoro-3H-pyrroles.

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