Journal
CHEMICAL COMMUNICATIONS
Volume -, Issue 20, Pages 2561-2563Publisher
ROYAL SOC CHEMISTRY
DOI: 10.1039/b500617a
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Among novel bis-nucleobase-phenanthridinium conjugates bis-uracil analogue 2 stabilized significantly more effective poly-dA - poly-dT and poly-AH(+)-poly-AH(+) than adenine analogue 3 and reference compound 1. For the alternating poly-dAdT-poly- dAdT however, the binding preference is lost, pointing to the importance of specific interactions of uracils of 2 with homopolynucleotides containing consecutive adenines.
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